Twelve passengers were injured and one reportedly broke their nose when their aircraft experienced severe turbulence.
An Aerolíneas Argentinas flight from Madrid, Spain, to Buenos Aires, Argentina, landed safely despite the incident, which left 12 out of 271 passengers injured, the company confirmed.
The plane took off at 8.21pm on October 18 from the Spanish capital and about seven hours later, while flying over Brazil, it was hit by turbulence.
The airline said seat belts signs were on and an announcement had been made, asking passengers to remain in their seats.
Nine passengers had to be treated for minor injuries and were released by airport health officials in Buenos Aires, Aerolíneas Argentinas said.
However, the company said three passengers did not wear their seat belts and on arrival, they had to be transferred to the hospital as they suffered more serious injuries.
The airline said the plane was not significantly damaged during the turbulence.
According to the Argentinian newspaper Los Andes, a woman suffered leg trauma without a fracture and another a man had a sharp head injury.
A statement shared by airline on social media says: "Aerolineas Argentinas reports that as a result of severe turbulence on flight AR 1133 from Madrid, which landed at Ezeiza airport at 4:30, 9 passengers had to be treated with various minor injuries.
"They were immediately released by airport health. Meanwhile, another three had to be transferred for a more exhaustive control.
"According to what was reported by the crew, the seat belt indicator signs were on and the corresponding announcement had been made.
"The passengers who were the most compromised and who were the ones who had to be transferred did not have their seat belts on at the time of the turbulence.
"The event occurred over the Atlantic Ocean entering the American continent and the plane, an A330 with registration LV-FVH, was carrying 13 crew members and 271 passengers.
"The evaluation of the aircraft did not show significant damage to its structure."