Sunday updates will begin when teams start releasing official pregame inactives and starter information to the league. This is typically around 90 minutes prior to the kickoff of their game.
Weather forecasts are courtesy of The Football Database.
Week 10 gameday inactives, weather and notes
KEY GAME-TIME DECISIONS
Early games: QB Trevor Lawrence (inactive), WR Brian Thomas Jr. (active), WR Deebo Samuel (active), RB Christian McCaffrey (active), WR Drake London (active), WR Amari Cooper (inactive)
Afternoon games:
Sunday night: WR Nico Collins (inactive)
Monday night: WR Tyreek Hill
Early games
New York Giants at Carolina Panthers in Munich (9:30 a.m. ET)
Kickoff Weather: 41°F, cloudy
Giants
Inactives: CB Jason Pinnock, DT Jordon Riley, QB Tommy DeVito, WR Darius Slayton, LB Darius Muasau, WR Bryce Ford-Wheaton and OG Jake Kubas
Lineup notes: WR Darius Slayton (concussion) is out. PK Graham Gano (hamstring) was activated from IR on Saturday.
Panthers
Inactives: DE Charles Harris, OT Ikem Ekwonu, CB Shemar Bartholomew, DT Jaden Crumedy, TE Tommy Tremble, S Jammie Robinson and RB Jonathon Brooks
Lineup notes: WR Adam Thielen (hamstring) is out again. RB Jonathon Brooks (knee) is inactive despite being close to playing. TE Ja’Tavion Sanders (wrist, ankle) managed a full session in Friday and will start at tight end. OT Ikem Ekwonu (ankle) is out.
New England Patriots at Chicago Bears (1:00 p.m. ET)
Kickoff Weather: 58°F, clear, SSW 12 mph
Patriots
Inactives: S Kyle Dugger, DL Eric Johnson, OL Tyrese Robinson, QB Joe Milton III, LB Christian Elliss, WR Tyquan Thornton and DL Yannick Ngakoue
Lineup notes: S Kyle Dugger (ankle) will not play.
Bears
Inactives: CB Ameer Speed, OT Darnell Wright, OT Kiran Amegadjie, LB Darrell Taylor, S Jaquan Brisker, OT Braxton Jones, OG Nate Davis and LB Noah Sewell
Lineup notes: CB Jayon Jones (shoulder) was placed on IR. S Jaquan Brisker (concussion), LT Braxton Jones (knee) and RT Darnell Wright (knee) are out.
Buffalo Bills at Indianapolis Colts (1:00 p.m. ET)
Kickoff Weather: 64°F, mostly cloudy (retractable-roof dome)
Bills
Inactives: WR Amari Cooper, LB Edefuan Ulofoshio, RB Reggie Gilliam, WR Keon Coleman, C Will Clapp and WR KJ Hamler
Lineup notes: WR Keon Coleman (wrist) has been ruled out. WR Amari Cooper (wrist) isn’t quite ready yet. TE Dalton Kincaid (knee) and QB Josh Allen (hand) practiced all week and will play.
Colts
Inactives: DL Adam Gotsis, WR Anthony Gould, WR Michael Pittman Jr., LB Genard Avery, QB Sam Ehlinger and CB Darren Hall
Lineup notes: C Ryan Kelly (knee) went on IR with a knee injury. WR Michael Pittman Jr. (back, finger) also is out.
Denver Broncos at Kansas City Chiefs (1:00 p.m. ET)
Kickoff Weather: 55°F, clear, WNW 11 mph
Broncos
Inactives: S Keidron Smith, OG Calvin Throckmorton, DT Eyioma Uwazurike, CB Kris Abrams-Draine, OT Frank Crum, QB Zach Wilson and TE Greg Dulcich
Lineup notes: No injuries of fantasy relevance.
Chiefs
Inactives: DT Marlon Tuipulotu, OG C.J. Hanson, OT Ethan Driskell, DE Cameron Thomas, WR JuJu Smith-Schuster and RB Clyde Edwards-Helaire
Lineup notes: RB Isiah Pacheco (leg), WR Rashee Rice (knee) and WR Skyy Moore (abdomen) are on IR. WR JuJu Smith-Schuster (hamstring) also is out. RB Kareem Hunt (quadriceps), WR Mecole Hardman (shoulder, knee) and QB Patrick Mahomes (ankle) all practiced Friday and will play.
Atlanta Falcons at New Orleans Saints (1:00 p.m. ET)
Kickoff Weather: Dome stadium
Falcons
Inactives: RB Jase McClellan, LB JD Bertrand, OG Jovaughn Gwyn, OT Brandon Parker, DE Brandon Dorlus, OT Elijah Wilkinson and LB Rashaan Evans
Lineup notes: WR Drake London (hip) will gut it out after being deemed questionable. LB Troy Andersen (knee) practiced all week and will play.
Saints
Inactives: QB Spencer Rattler, WR Cedrick Wilson, DT Khristian Boyd, CB Kool-Aid McKinstry, RB Jamaal Williams, OG Lucas Patrick and LB Jaylan Ford
Lineup notes: RB Kendre Miller (hamstring) landed back on IR with an injury to the hamstring in his other leg. WR Chris Olave (concussion) will join him, and WR Cedrick Wilson (shoulder) was ruled out. RB Jamaal Williams (groin) is inactive. QB Derek Carr (illness) and RB Alvin Kamara (hand) practiced all week and will play.
San Francisco 49ers at Tampa Bay Buccaneers (1:00 p.m. ET)
Kickoff Weather: 82°F, cloudy, ESE 10 mph
49ers
Inactives: DT Kevin Givens, OG Ben Bartch, TE Brayden Willis, CB Charvarius Ward, WR Chris Conley and QB Joshua Dobbs
Lineup notes: RB Christian McCaffrey (Achilles) will play after Saturday’s activation from IR. WR Deebo Samuel (rib, oblique) and DE Nick Bosa (hip) will give it a go after earning questionable designations. RB Jordan Mason (shoulder), PK Jake Moody (ankle) and WR Jauan Jennings (hip) practiced Friday and will go.
Buccaneers
Inactives: LB Antonio Grier, DE Jose Ramirez, WR Mike Evans, TE Devin Culp, DE Earnest Brown, S Tykee Smith and OG Royce Newman
Lineup notes: WR Chris Godwin (ankle) remains on IR and will miss the rest of the season. WR Mike Evans (hamstring) is out again WR Jalen McMillan (hamstring) is active following Friday’s questionable designation. RB Bucky Irving (toe), WR Sterling Shepard (hamstring, hip) and QB Baker Mayfield (toe) will all play.
Pittsburgh Steelers at Washington Commanders (1:00 p.m. ET)
Kickoff Weather: 60°F, cloudy, S 11 mph
Steelers
Inactives: OT Max Scharping, WR Scotty Miller, CB CJ Henderson, QB Kyle Allen and LB Nick Herbig
Lineup notes: No injuries of fantasy relevance.
Commanders
Inactives: CB Marshon Lattimore, PK Austin Seibert, OT Cornelius Lucas, QB Jeff Driskel, S Darrick Forrest Jr., S Dominique Hampton and RB Brian Robinson Jr.
Lineup notes: CB Marshon Lattimore (hamstring) and RB Brian Robinson Jr. (hamstring) are out. PK Austin Seibert (hip) was downgraded to out, so PK Zane Gonzalez will handle the kicking chores. RT Andrew Wylie (shoulder) will play. RB Chris Rodriguez Jr. was elevated to the active roster.
Minnesota Vikings at Jacksonville Jaguars (1:00 p.m. ET)
Kickoff Weather: 77°F, cloudy
Vikings
Inactives: DT Levi Drake Rodriguez, OG Dan Feeney, CB Dwight McGlothern, DB Fabian Moreau, QB Brett Rypien and OT Walter Rouse
Lineup notes: No injuries of fantasy relevance.
Jaguars
Inactives: OL Ezra Cleveland, DT Maason Smith, QB Trevor Lawrence, LB Myles Cole and DE Esezi Otomewo
Lineup notes: WR Christian Kirk (collarbone) remains on IR and is likely out for the season. OG Ezra Cleveland (ankle) is out again. QB Trevor Lawrence (shoulder) will not be available, meaning QB Mac Jones draws the start. WR Brian Thomas Jr. (chest), WR Gabe Davis (shoulder) and RB Keilan Robinson (toe) are all active. RB Tank Bigsby (ankle) also was limited this week, but he doesn’t carry an injury designation. WR Devin Duvernay (hamstring) was activated from IR and will play.
Late-afternoon window
Tennessee Titans at Los Angeles Chargers (4:05 p.m. ET)
Kickoff Weather: 68°F, clear (open-air dome)
Titans
Inactives: CB L’Jarius Sneed, TE David Martin-Robinson, CB Gabe Jeudy-Lally, LB Cedric Gray, RB Joshua Kelley and S Mike Edwards
Lineup notes: WR Treylon Burks (knee) remains on IR. CB L’Jarius Sneed (quad) will not play. RB Tyjae Spears (hamstring), WR Tyler Boyd (shoulder), QB Will Levis (shoulder) and RB Tony Pollard (foot) will all play. Pollard was limited Friday, but the rest were full participants.
Chargers
Inactives: DE Justin Eboigbe, TE Stone Smartt, RB Kimani Vidal, CB Kristian Fulton, OT Trey Pipkins, QB Easton Stick and OG Jordan McFadden
Lineup notes: RB Gus Edwards (ankle) came off IR and will play. LB Joey Bosa (hip) and LB Khalil Mack (groin) are active despite being questionable.
Philadelphia Eagles at Dallas Cowboys (4:25 p.m. ET)
Kickoff Weather: 76°F, clear
Eagles
Inactives: OG Darian Kinnard, QB Tanner McKee, CB Eli Ricks, OG Trevor Keegan and DB Tristin McCollum
Lineup notes: TE Dallas Goedert (hamstring), WR A.J. Brown (knee) and WR DeVonta Smith (hamstring) will all play. Smith was out of practice Wednesday, limited Thursday and a full-go Friday. Brown was limited Wednesday and good the rest of the week.
Cowboys
Inactives: QB Dak Prescott, CB DaRon Bland, WR Jonathan Mingo, OT Tyler Guyton, RB Deuce Vaughn, S Juanyeh Thomas and DL K.J. Henry
Lineup notes: WR Brandin Cooks (knee) remains on IR. QB Dak Prescott (hamstring), LT Tyler Guyton (neck, shoulder), and CB DaRon Bland (foot) are out. DE Micah Parsons (ankle), WR CeeDee Lamb (shoulder), and RG Zack Martin (shoulder) will play.
New York Jets at Arizona Cardinals (4:25 p.m. ET)
Kickoff Weather: 77°F, clear (retractable-roof dome)
Jets
Inactives: OT Carter Warren, RB Israel Abanikanda, C Jake Hanson, LB C.J. Mosley and DE Solomon Thomas
Lineup notes: LB C.J. Mosley (neck) is inactive. TE Tyler Conklin (ankle) and RT Morgan Moses (knee) are active. QB Aaron Rodgers (knee, hamstring) will start.
Cardinals
Inactives: S Jalen Thompson, DL Darius Robinson, TE Travis Vokolek, DL Julian Okwara, WR Xavier Weaver and OT Christian Jones
Lineup notes: PK Matt Prater (knee) remains on IR. S Jalen Thompson (ankle) will not be available. RB James Conner (finger) practiced Friday and will play.
Sunday Night Football
Detroit Lions at Houston Texans (8:20 p.m. ET)
Kickoff Weather: 77°F, clear (retractable-roof dome)
Lions
Inactives: OT Colby Sorsdal, DB Loren Strickland, OT Taylor Decker, LB Malcolm Rodriguez, OT Giovanni Manu, DL Za’Darius Smith and OG Christian Mahogany
Lineup notes: LT Taylor Decker (shoulder) is out.
Texans
Inactives: CB Myles Bryant, DL Will Anderson Jr., WR Nico Collins, RB Dameon Pierce, OG Zachary Thomas and LB Jamal Hill
Lineup notes: WR Stefon Diggs (hamstring) is out for the year with a torn ACL. DE Will Anderson Jr. (ankle) and RB Dameon Pierce (groin) are out. WR Nico Collins (hamstring) was close to returning but is indeed inactive. WR Tank Dell (back) will play, however.
Monday Night Football
Miami Dolphins at Los Angeles Rams (8:15 p.m. ET)
Kickoff Weather: 61°F, clear (open-air dome)
Dolphins
Lineup notes: WR Tyreek Hill (wrist) didn’t practice Friday. Watch his participation level Saturday. RT Austin Jackson (knee) will not be available to protect QB Tua Tagovailoa‘s blindside.
Rams
Lineup notes: TE Tyler Higbee (knee) remains on the PUP. WR Jordan Whittington (shoulder) and WR Demarcus Robinson (toe, hip) avoided injury tags.
