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Medical Daily
Medical Daily
Joseph James

Estimated 48% of Women with Heavily Treated Ovarian Cancer Were Alive at Three Years in Small Immunotherapy Trial

Women whose ovarian cancer keeps coming back after several rounds of treatment rarely hear encouraging survival numbers. New three-year follow-up from a small, early-stage trial offers one, with important limits attached. An estimated 48% of patients treated with an experimental pair of immunotherapy drugs were alive three years after starting treatment, the same estimate researchers reported at the two-year mark.

The results come from the ovarian cancer group of the phase 1b C-800-01 trial, which tested botensilimab together with balstilimab. The data were presented on October 3 at the International Gynecologic Cancer Society's 2026 Annual Global Meeting in Montréal, Canada, according to drug developer Agenus. Only 35 patients were included in the effectiveness analysis; the study had no comparison group, and neither drug is approved by the FDA.

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