Erik ten Hag has warned the fringe players in Manchester United's squad must be ready to contribute when called upon.
United play Southampton in the Premier League on Saturday afternoon and Ten Hag is expected to make minimal changes to the line up that started against Liverpool on Monday, which included Raphael Varane and Lisandro Martinez at centre-back.
However, new signing Casemiro was officially unveiled before that game and he is expected to start at St. Mary's Stadium, while Cristiano Ronaldo could return to the starting XI after Marcus Rashford played down the middle against Liverpool.