The Ebola outbreak spreading across the Democratic Republic of the Congo and Uganda has become one of the most serious in recorded history, and the United States government is responding at its highest level of emergency activation.
On June 26, 2026, the CDC elevated its Ebola response to a Level One activation, the most intensive emergency response classification in the agency's incident management system. The announcement came as the DRC Ministry of Health confirmed the outbreak has surpassed 1,100 cases and 300 deaths across DRC and Uganda, making it the third-largest Ebola outbreak ever documented, behind only the 2014–2016 West Africa epidemic and the 2018–2020 DRC outbreak.