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The Conversation
The Conversation
Rahul Sidhu, PhD Candidate, Neuroscience, University of Sheffield

Early-onset Alzheimer’s: new drug shows promise in slowing the disease

The drug also caused a notable decrease in amyloid plaque buildup, which is a hallmark of Alzheimer's disease. ART-ur/ Shutterstock

Alzheimer’s disease is usually associated with old age. But around 5%-10% of all Alzheimer’s cases occur in people under the age of 65. Early-onset Alzheimer’s disease progresses more rapidly and often strikes people in the prime of their lives. Treatment options remain limited.

But new data from a recent clinical trial suggests that a previously discontinued experimental drug, called gantenerumab, could help. The study found that gantenerumab reduced the buildup of amyloid plaques – one of the hallmarks of Alzheimer’s disease – in the brain. This may help slow cognitive decline in people with early-onset Alzheimer’s.

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