Dumfries and Galloway recorded 570 cases of fly-tipping in the 12 months to January 2023.
The shock figures were revealed in a nationwide survey of local authorities by the Scottish Conservatives.
Local MSP Finlay Carson described the situation as “wholly unacceptable” – and called for tougher measures.
He said: “It is horrifying to think that some people find fly-tipping as being acceptable despite the misery and problem it often causes.
“They seem to believe they can just dump it wherever they like and simply pass on their mess for someone else to clean up.
“In particular, if the rubbish is dumped on private land it is left to the owner or possibly even a farmer to sort it out.
“Sometime in the case of hazardous materials, they are putting the lives of others at risk because the fly-tippers do not want to deal with it themselves.”
He added: “We need to deal with this urgently and bring in a raft of measures to discourage this behaviour.
“Tough action needs to be taken and quickly before the situation gets even worse.”
A Member’s Bill on fly-tipping, being brought forward to Holyrood by Murdo Fraser MSP, has secured cross party support.
If passed it would strengthen the law and toughen punishments for breaching it.
More than 60,000 instances of fly-tipping were recorded in Scotland last year.