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The Guardian - UK
The Guardian - UK
Science
Simon Spichak

Does the microbiome hold the key to chronic fatigue syndrome?

Image of viruses and molecules surrounding a colon and intestines
Illustration by Observer Design/Science Photo Library/Getty; Alamy. Composite: Science Photo Library/Getty; Alamy

In 2019, years after developing the myalgic encephalomyelitis (ME/CFS) that had kept her bedridden in a state of chronic pain and exhaustion, Tamara Romanuk experienced something “miraculous”. After taking antibiotics prescribed to treat a separate infection, she experienced a short-term remission in symptoms. “I went from being bedbound to twirling outside,” Romanuk says. “I had no idea that life could be so different from what I’d become adjusted to.”

Sharing her experience online, Romanuk, a former biology professor, discovered that she wasn’t the only person who had had this experience. Both she and Tess Falor, an engineer with a PhD, had developed ME/CFS years before and had picked up a bacterial infection that required antibiotic treatment. Doctors had advised them to take probiotic supplements to help the microbiome recover. Afterwards, both experienced a dramatic remission in ME/CFS symptoms. They called it a “remission event”. Romanuk and Falor have named their project to investigate the experience the RemissionBiome.

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