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The Guardian - UK
The Guardian - UK
Entertainment
James Ball

Doctored by Charles Piller review – the scandal that derailed Alzheimer’s research

Research into Alzheimer's and dementia has been set back by the use of fraudulent evidence.
The amyloid hypothesis has dominated research into Alzheimer’s disease. Photograph: Science Photo Library/Alamy

Living to old age is quite literally the best thing that any of us could hope for, given the alternative. It’s a cruel irony, then, that many of us who make it that far will begin to lose our sense of who we are due to dementia. If you’re 65, you’ve got about a one in 20 chance of developing the most common form, Alzheimer’s disease, in the next decade. At 75, it’s about one in seven, while those fortunate enough to reach 85 face a one in three chance.

Given the toll this illness takes on sufferers and those around them, hundreds of millions of families around the world are desperate for a medical breakthrough – and for years, headlines have suggested that it might be imminent. Scientists had identified the cause of Alzheimer’s, they promised, and potential cures were already being tested.

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