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The Guardian - UK
The Guardian - UK
Politics
Ian Sample Science editor

Do gut microbes have a role in autism itself?

A computer illustration of Lactobacillus bacteria (depicted in red and orange), the main component of the human small intestine microbiome.
About 80% of autism is thought to be down to DNA, but researchers are investigating a number of potential factors such as the gut microbiome.
Photograph: Science Photo Library/Alamy

Wind the clock back 40 years and autism, at least officially, was a rare condition. According to case rates in the 1980s, only a handful of people in every 10,000 received a diagnosis. The picture today is radically different: better awareness and a broadening of the criteria mean autism is now common – 1% to 3% of people worldwide are now estimated to be on the autism spectrum.

History records some horrendous mistakes around the underlying causes of the condition. One of the earliest studies of autistic children remarked that many had “highly intelligent parents” and close relatives who were “limited in genuine interest in people”. The observation fuelled the false and deeply damaging idea that autism was caused by “refrigerator parents” – a coldness in the upbringing.

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