Diagnostic dilemma: A rare condition caused a man to get 'scales' on his hands whenever he washed them

Hands of man with rare skin condition.

The patient: A man in his 20s in China

The symptoms: A man went to the dermatology department of a hospital after experiencing an array of symptoms for about three years. When he submerged his hands in water, such as during hand-washing, the skin on the back of the man's hands thickened and became overly wrinkly, with white bumps and growths appearing.