Darwin Nunez is in contention for Liverpool's season finale with Jurgen Klopp set to give an opportunity to a number of fringe players.
The Reds end their Premier League campaign at Southampton in the knowledge they will finish fifth - their lowest placing since 2016 - with their opponents having already been relegated in last place.
Nunez has been absent for the last two games with a minor toe complaint but returned to training this week at Kirkby. Andy Robertson, though, has had a scan on a groin problem while Ibrahima Konate has been suffering from illness.
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And while Klopp will not be guided by sentiment in offering farewell appearances to Liverpool's clutch of departing players, there will be a number of changes.
"We will not take any risks with players, let me say it like this, that makes now no sense," said the Reds boss. "But we have a big group together and the training week looked really good, the boys bought really into it, that was cool.
"But I didn’t make any kind of decisions because it’s now pretty early and I didn’t see the doc yet. I will have a brief conversation with him and then we will see who is in contention, and when we have that then I have to make sure we find players who are really in all departments ready for the game.
“He (Nunez) trained yesterday, fully. Ibou was ill yesterday. Robbo felt something in his groin yesterday, he had a scan, that was fine but we anyway have to see how we can deal with that. Long-term are still out, that’s clear. The rest should be all right.”
It means Naby Keita has now played his last game for Liverpool having not featured since being substituted at half-time at Crystal Palace in February.
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Of the other imminent departures, James Milner and Roberto Firmino could be in contention for a start while Alex Oxlade-Chamberlain and on-loan Arthur Melo may have to settle for a place on the bench at best.
Kostas Tsimikas, Joel Matip, Joe Gomez, Harvey Elliott and Diogo Jota are all pressing for a place in the XI while Caoimhin Kelleher could replace Alisson Becker in goal.
"I think it makes sense that we make changes, to be honest, just to get fresh legs on the pitch," said Klopp. "And players who want to show something, besides the fact that we anyway want to win the game, that’s clear.
"I’m not used to games on the last matchday where everything is sorted before, I cannot remember when that last time was the case, usually we play until the last matchday and everything is at stake pretty much.
"But football, we only play this game to win the game, that’s the only reason we meet. And we have to make sure that I find a line-up with good legs, a lot of desire. And we have to see."
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