A dad-of-four who had a pain in his side and then found a lump in his shoulder spent a year seeing multiple specialists who told him he had cancer, but they didn't know where. Construction worker Chris Russell, 54, was told the lump was a secondary tumour, meaning he had cancer that had spread from where it first originated - but medics could not find where the cancer originally came from.
Chris was told he had cancer of unknown primary (CUP) - the sixth most common cause of cancer death. Without knowing the location of the original tumour, doctors can only give a combination of chemotherapy drugs used to treat a broad range of cancers.
There are no approved immunotherapies or targeted treatments for CUP outside of clinical trials, reports MEN.