Liverpool have a chance to get early revenge on Real Madrid following last season's Champions League final heartbreak after being drawn against them in the Round of 16.
In arguably the tie of the draw, Jurgen Klopp's side must come out on top against Carlo Ancelotti's men over two legs after they beat them 1-0 in Paris just six months ago.
Pep Guardiola's Manchester City face an easier test in RB Leipzig. Elsewhere, Graham Potter Chelsea's play Dortmund, while Antonio Conte and Tottenham have been drawn against AC Milan.