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Diego E. Rincon-Limas, Associate Professor of Neurology, University of Florida

Brain inflammation may be the reason behind muscle fatigue after infection and injury

Neuroinflammation is a result of your central nervous system's immune response. nopparit/E+ via Getty Images

Infectious or chronic diseases such as long COVID, Alzheimer’s disease and traumatic brain injury can cause inflammation in the brain, or neuroinflammation, that weakens muscles. While scientists are aware of this link between inflammation and muscle weakness, the molecules and processes involved have been unclear.

In our research, our team of neuroscientists and biologists uncovered the hidden conversation between the brain and muscles that triggers muscle fatigue, and potential ways to treat it.

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