
Borderlands 4 is an FPS, sure, but first and foremost it's an ARPG—with all the intersecting build shenanigans you'd come to expect. Players have already started uncovering a few of these—for instance, if you get the right knife, you can basically instagib anything.
See, throwing knives can have the "Penetrator Augment" rolled on them, which causes all damage to be critical damage for a few seconds. Vex, in particular, can combine this with her Contamination skill, with critical hits causing 100% status chance, stacked on top of her crits already being able to cause bleeds. You bleed someone, the bleed is now critically hitting, causing more bleeds, which themselves cause more bleeds, which then—you get the idea.