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USA Today Sports Media Group
Sport
Joe Vitale

Betting lines, score predictions for college football’s top Week 1 games

College football is officially back.

Week 1 of the 2022 season brings us some exciting matchups, with none bigger than No. 2 Ohio State hosting No. 5 Notre Dame.

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Georgia, the defending national champions, also plays Oregon in Atlanta on Saturday. The fun continues on Sunday with FSU vs. LSU and again on Monday when Clemson plays Georgia Tech.

If you’re looking to do some last-minute betting research on this week’s biggest games, you’re in luck! We’ll give you the latest point spread, money line odds and over/under number, as well as the information you’ll need to make the smartest bet at Tipico Sportsbook.

The lines, courtesy of Tipico Sportsbook

Thursday, Sept. 1: West Virginia at #17 Pitt

Bob Donnan-USA TODAY Sports

The bets:

Spread: Pitt -7.5 (-103), West Virginia +7.5 (-117)

Money: Pitt -300, West Virginia +230

Over/Under: 51.5 (-103 over, -117 under)

The game:

Thursday, Sept. 1, 7 p.m. ET on ESPN, Acrisure Stadium, Pittsburgh, PA

The prediction:

Pitt 38, WVU 17

Thursday, Sept. 1: Penn State at Purdue

Matthew OHaren-USA TODAY Sports

The bets:

Spread: Penn State -3.5 (-108), Purdue +3.5 (-112)

Money: Penn State -180, Purdue +145

Over/Under: 54.5 (-105 over, -115 under)

The game:

Thurs, Sept. 1, 8 p.m. ET on FOX, Ross-Ade Stadium, West Lafayette, IN

The prediction:

Penn State 24, Purdue 17

Saturday, Sept. 3: Colorado State at #8 Michigan

Dylan Widger-USA TODAY Sports

The bets:

Spread: Michigan -30.5 (-115), Colorado State +30.5 (-105)

Money: Michigan -5,000, Colorado State +1,300

Over/Under: 61.5 (-112 over, -108 under)

The game:

Saturday, Sept. 3, 12 p.m. ET on ABC, Michigan Stadium, Ann Arbor, MI

The prediction:

Michigan 45, Colorado State 17

Saturday, Sept. 3: UNC at App State

Rob Kinnan-USA TODAY Sports

The bets:

Spread: App State -0.5 (-110), UNC +0.5 (-110)

Money: App State -110, UNC -110

Over/Under: 56.5 (-108 over, -112 under)

The game:

Saturday, Sept. 3, 12 p.m. ET on ESPNU, Kidd Brewer Stadium, Boone, NC

The prediction:

UNC 31, App State 27

Saturday, Sept. 3: #13 NC State at ECU

Rob Kinnan-USA TODAY Sports

The bets:

Spread: NC State -11.5 (-105), ECU +11.5 (-115)

Money: NC State -450, ECU +330

Over/Under: 54.5 (-117 over, -103 under)

The game:

Sat, Sept. 3, 12 p.m. ET on ESPN, Dowdy-Ficklen Stadium, Greenville, NC

The prediction:

NC State 31, ECU 10

Saturday, Sept. 3: #23 Cincinnati at #19 Arkansas

Jay Biggerstaff-USA TODAY Sports

The bets:

Spread: Arkansas -6.5 (-105), Cincinnati +6.5 (-115)

Money: Arkansas -240, Cincinnati +190

Over/Under: 51.5 (-115 over, -105 under)

The game:

Sat, Sept. 3, 3:30 p.m. ET on ESPN, Razorback Stadium, Fayetteville, AR

The prediction:

Arkansas 30, Cincinnati 24

Saturday, Sept. 3: #3 Georgia vs. #11 Oregon

Sam Navarro-USA TODAY Sports

The bets:

Spread: Georgia -17.5 (-108), Oregon +17.5 (-112)

Money: Georgia -900, Oregon +570

Over/Under: 52.5 (-112 over, -108 under)

The game:

Saturday, Sept. 3, 3:30 p.m. ET on ABC, Mercedes-Benz Stadium, Atlanta, GA

The prediction:

Georgia 24, Oregon 10

Saturday, Sept. 3: #7 Utah at Florida

Stephen Lew-USA TODAY Sports

The bets:

Spread: Utah -2.5 (-120), Florida +2.5 (+100)

Money: Utah -150, Florida +122

Over/Under: 50.5 (-115 over, -105 under)

The game:

Sat, Sept. 3, 7 p.m. ET on ESPN, Ben Hill Griffin Stadium, Gainesville, FL

The prediction:

Utah 30, Florida 27

Saturday, Sept. 3: Utah State at #1 Alabama

Butch Dill-USA TODAY Sports

The bets:

Spread: Alabama -41.5 (-105), Utah State +41.5 (-115)

Money: N/A

Over/Under: 62.5 (-105 over, -115 under)

The game:

Sat, Sept. 3, 7:30 p.m. ET on SECN, Bryant-Denny Stadium, Tuscaloosa, AL

The prediction:

Alabama 55, Utah State 13

Saturday, Sept. 3: #5 Notre Dame at #2 Ohio State

Syndication: The Columbus Dispatch

The bets:

Spread: Ohio State -17.5 (-105), Notre Dame +17.5 (-115)

Money: Ohio State -850, Notre Dame +550

Over/Under: 58.5 (-110 over, -110 under)

The game:

Saturday, Sept. 3, 7:30 p.m. ET on ABC, Ohio Stadium, Columbus, OH

The prediction:

Ohio State 38, Notre Dame 24

Sunday, Sept. 4: Florida State vs. LSU

Dale Zanine-USA TODAY Sports

The bets:

Spread: LSU -2.5 (-130), FSU +21.5 (+105)

Money: LSU -160, FSU +130

Over/Under: 51.5 (-110 over, -110 under)

The game:

Sun, Sept. 4, 7:30 p.m. ET on ABC, Caesars Superdome, New Orleans, LA

The prediction:

LSU 31, FSU 27

Monday, Sept. 5: #4 Clemson vs. Georgia Tech

(Photo by Grant Halverson/Getty Images)

The bets:

Spread: Clemson -21.5 (-110), Georgia Tech +21.5 (-114)

Money: Clemson -2000, Georgia Tech +800

Over/Under: 48.5 (-114 over, -110 under)

The game:

Monday, Sept. 5, 8 p.m. ET on ESPN, Mercedes-Benz Stadium, Atlanta, GA

The prediction:

Clemson 42, Georgia Tech 10


Click here to place your bets at Tipico Sportsbook.

Get more betting analysis and predictions at Sportsbook Wire.

Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO).

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