
SAM-e, short for S-adenosyl-L-methionine, is a naturally occurring compound in the body that has gained attention for its potential health benefits. Discovered in 1952, SAM-e plays a crucial role in various biochemical processes, including the synthesis of neurotransmitters, DNA methylation, and the maintenance of cell membranes. This compound is found in every cell of the body and is particularly abundant in the liver, where it plays a vital role in liver function and detoxification. As a dietary supplement, SAM-e has been studied for its potential to support mood, joint health, liver function, and cognitive health. Here's a closer look at the benefits, uses, and mechanisms of SAM-e.