Nineteen points from Benetton fly-half Tomas Albornoz condemned the Scarlets to a defeat in Italy as a late comeback from the Welsh side fell short.
Late tries from Sione Kalamafoni and Johnny Williams gave the Scarlets hope late on, although their injury worries appeared to deep as they lost both Williams and Josh Macleod. Having welcomed back Leigh Halfpenny and Ken Owens in Italy after long-term injuries, Macleod was forced injured just a couple of minutes into his 100th appearance for the Scarlets, while Williams also limped off.
The home side opened the scoring after five minutes after Vaea Fifita was penalised on the deck, with Albornoz slotting over the early penalty.