Mikel Arteta has heavily rotated his Arsenal's line-up as the quadruple bid begins away at Ipswich in the Carabao Cup third round.
The Gunners have made a strong start to the season, winning all five matches domestically and in Europe, and Arteta now looks set to make full use of his deep squad at Portman Road.
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Second-choice keeper Kepa Arrizabalaga gets the nod over third-choice Illan Meslier to start in the cup, with David Raya given the night off.
Riccardo Calafiori, Declan Rice, Bukayo Saka and Martin Odegaard are among those who are also in line to be rested. Of those four, Rice is left out of the squad altogether with the other three named to the bench.
With Ben White an injury concern after coming off on Saturday night against Sunderland, Arteta is short of options at right-back.
Jurrien Timber has only just returned from his long absence, but Arteta has declined the opportunity to build his fitness here. He is left out of the squad.
Cristhian Mosquera also misses out with a muscle problem. Piero Hincapie is an option to fill in at centre-back and Myles Lewis-Skelly could be shifted out to left-back.
Martin Zubimendi gets his chance in midfield after limited involvement so far this season. He starts next to Bruno Guimaraes.
In attack, Noni Madueke replaces Saka on the right wing, and Eze is the obvious candidate to start on the other flank. Max Dowman also gets the nod.
Viktor Gyokeres leads the line and Arteta will hope it is an opportunity for his striker to get on the scoresheet and build some confidence after a frustrating start to the season.
Arsenal XI: Arrizabalaga; Salmon, Gabriel, Lewis-Skelly, Zubimendi, Guimaraes, Merino, Dowman, Madueke, Eze, Gyokeres
Subs: Meslier, Saka, Odegaard, Konsa, Tzolis, Havertz, Calafiori, Ibrahim, Julienne
Injured: Saliba, White, Mosquera
Time and date: 8pm BST on Tuesday, September 15, 2026
Venue: Portman Road
How to watch: Sky Sports
