Granit Xhaka misses out for Arsenal in their Premier League clash against Southampton at the Emirates Stadium. The Swiss international is absent due to illness and replaced in the starting XI by Fabio Vieira.
It's one of two changes to the side who drew 2-2 with West Ham last week. Kieran Tierney is back among the subs with Oleksandr Zinchenko straight back in the team after his groin injury.
That means that William Saliba is absent once again, with Rob Holding continuing into the side. There is hope that the Frenchman could be back for Manchester City on Wednesday, although Mikel Arteta refused to rule out the possibility he could be out for the season.