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Andrew McLean, Clinical Professor of Psychiatry and Behavioral Science, University of North Dakota

Are too many Americans taking antidepressants?

Rates of anxiety and depression have grown since the COVID-19 pandemic – as have prescriptions for antidepressants. brizmaker/iStock via Getty Images Plus

Drugs for treating depression are among the most prescribed category of medications in the U.S. – 1 in 6 American adults take them.

Some health researchers and advocates have raised concerns that too many patients are using antidepressants and that patients who want to stop taking them struggle to do so. One of the most prominent voices on this point is Health and Human Services Secretary Robert F. Kennedy Jr., who launched an effort in May 2026 encouraging doctors to find other ways besides antidepressants and other psychiatric drugs to treat depression when possible.

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