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Silvia Maioli, Associate professor and Principal Researcher, Neurobiology, Karolinska Institutet

Alzheimer’s: certain combinations of prescription drugs may slow progression of the disease, says mice study

Certain prescription drugs combinations had different effects on the mice. roger ashford/ Shutterstock

Millions of older adults take five or more prescription drugs every day to manage chronic illnesses. While polypharmacy is often necessary, this practice has also been linked to many negative health outcomes in older adults – including memory problems, increased risk of falls and greater frailty.

The most common prescription drugs involved in polypharmacy are those used to treat conditions such as high blood pressure, high cholesterol and depression. Importantly, these same conditions are also known risk factors for Alzheimer’s disease.

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