Prohibition makes drug use more dangerous by creating a black market in which quality and potency are highly variable and unpredictable. Ramped-up enforcement of prohibition magnifies that problem, as dramatically demonstrated by the deadly impact of restricting access to pain medication at the same time that illicit fentanyl was proliferating as a heroin booster and substitute. That sort of perverse effect pervades drug law enforcement, as illustrated by a new study that found drug seizures in San Francisco were associated with a substantial increase in overdose risk.
The study included 2,653 drug seizures and 1,833 opioid-related deaths from 2020 to 2023. "Within the surrounding 100, 250, and 500 meters," RTI International researcher Alex H. Kral and his two co-authors reported in JAMA Network Open on Wednesday, "drug seizures were associated with a statistically significant increase in the relative risk for fatal opioid overdoses."
That is not the result that local authorities expected. "Since fentanyl entered the unregulated drug supply in San Francisco, California, around 2019, overdose mortality rates have reached record highs," Kral et al. note. "This has sparked increased enforcement of drug laws."