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Medical Daily
Medical Daily
Cole Mercer

A New Pancreatic Cancer Drug Is Reaching Patients Before Approval and the Testing Rules Are Not What Many Assume

Patients with previously treated metastatic pancreatic cancer are receiving an investigational drug that has not yet been approved, through a federal pathway that opened this spring.

The drug is daraxonrasib, an oral RAS inhibitor developed by Revolution Medicines. In the Phase 3 RASolute 302 trial, patients receiving it had a median overall survival of 13.2 months in the overall study population, compared with 6.7 months for those receiving standard chemotherapy, a 60 percent reduction in the risk of death.

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