San Francisco running back Christian McCaffrey sustained a knee injury during the 49ers' 35-10 loss to the Buffalo Bills on Sunday night. Head coach Kyle Shanahan expressed concerns that the injury could be season-ending. McCaffrey is believed to have injured his posterior cruciate ligament, which connects the thigh bone to the shin. Shanahan mentioned that there is no definitive timeline for McCaffrey's return, but acknowledged the possibility of his season being over.
This injury adds to a challenging season for McCaffrey, who missed the first eight games due to Achilles tendinitis and has struggled to regain his form since returning. The setback comes at a difficult time for the 49ers, who have been plagued by injuries throughout the season and were missing five starters in the game against Buffalo.
