
The 49ers are dealing with a slew of significant injuries after Sunday night’s loss to the Denver Broncos. They could be without starters Trent Williams and Azeez Al-Shaair for a significant stretch of games.
Head coach Kyle Shanahan on Monday in a conference call with reporters said Williams has a high ankle sprain that could keep him out between four and six weeks, although he expressed some uncertainty when asked about a specific timeframe for Williams’ return.