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Marie Claire
Marie Claire
Lifestyle
Siena Gagliano

111Skin's $825 Exosome Duo Promises a “Face Lift” in a Bottle—Here’s the Truth

111 Skin exosome therapy serum duo.

I’ll be honest: As a beauty editor, I know the drill when it comes to luxury skincare prices. But the $825 111SKIN Exosome Face Lift Duo made even me pause. At nearly the cost of a weekend getaway, a fancy purse, or even filler and Botox, it sits firmly in this-better-do-something territory. And because I’m a curious girl who wants to bust beauty BS and find out what's actually worth it, I committed to the full four-week protocol: a two-step treatment, beginning with the Exosome Shot Serum every night, followed by the rich Overnight Mask that seals everything in while I sleep.

I went into it skeptical, but because of my background knowledge in cosmetic chemistry, I knew the treatment was filled with legit ingredients. Exosomes, the tiny messengers that help cells communicate and support repair, are a buzzy—but scientifically grounded—concept in skincare. Still, I’ve tested enough trendy beauty products to know that claims of quick-acting results don’t usually pan out. Yet within about 10 days, I started noticing something I didn’t expect: a slightly firmer appearance around my cheekbones and along my jawline. It was slight, but it definitely made me do a double-take. My skin also felt tighter and lifted, with a subtle glow.

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