More than 100 vulnerable children were vaccinated at Alder Hey Children's Hospital over the weekend following recommendations from the NHS.
110 children who are considered at higher risk of serious complications of Covid-19 were vaccinated at the children's hospital.
The NHS recently recommended children aged five to 11 who are considered at higher risk of serious complications of Covid-19 should be offered two paediatric doses of the vaccine eight weeks apart.
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The chief nursing officer at the children's hospital told the ECHO the health service is still learning about the long-term damage of the virus.
They added with infection rates still relatively high, "the vaccine is the best way to protect our vulnerable children from Covid-19".
Due to the potential long term risks of the virus, the NHS has recommended children with weaker immune systems to be vaccinated.
Vulnerable children who have severe neurodisabilities, profound and multiple or severe learning disabilities, Down's syndrome, on the learning disability register, or with long term serious conditions have also been recommended.
Information from Alder Hey Children's Hospital also said the vaccine is also being offered to children living with people who have a weakened immune system to reduce the risk of passing the infection to family members.
Further clinics will be offered by staff from Alder Hey Children's Hospital at a number of locations across Merseyside.
Nathan Askew, Chief Nursing Officer at Alder Hey Children's Hospital said: "This weekend Alder Hey have been busy vaccinating vulnerable 5-11 year olds or children who live with vulnerable adults.
"The Covid-19 virus is still out there and infection rates are relatively high.
"Young people are missing out on the things they want to do because of covid-related illness and we are still learning about the long-term damage the virus can do.
"The vaccine is the best way to protect our vulnerable children from Covid-19."
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